Mariette van Huijstee specialises in the international normative framework in the field of business and human rights, in particular the United Nations Guiding Principles on Business and Human Rights. She examines how companies and governments implement their responsibilities and obligations to respect human rights. She presses for enforceable instruments at the international level. She also conducts research into the effectiveness of complaint mechanisms and calls for better access to compensation for victims of human rights abuses by companies. Mariette also advises and trains civil society organisations in developing different strategies to secure respect for human rights and environment in the private sector.

Mariëtte holds a PhD in Environmental Policy from Utrecht University. Her dissertation focused on how NGOs influence businesses to ensure corporate responsibility.